In 1895, Dracula builds a resort in Transylvania, hidden from the humans, to raise his beloved daughter Mavis in a safe environment. In the present days, the place is the Hotel Transylvania, where monsters bring their families to spend vacation far from the frightening humans. Dracula invites his friends - Frankenstein and his wife Eunice; Wayne and Wanda, the werewolves; Griffin, the invisible man; Murray, the mummy; the Bigfoot, among others - to celebrate the 118th birthday of Mavis. When the party is ready to start, the 21-year-old Jonathan is walking through the forest and stumbles at the hotel. Dracula sees Jonathan and disguises him as a monster to hide Jonathan from the guests. But Mavis also sees Jonathan and Dracula forces him to pose of a monster. Soon Mavis believes that Jonathan is the "zing" of her life despite the advices of her father about the humans.